ORX is a Casual, RPG, and Simulation game for PC published by CRITICAL REFLEX in 2022. Good use of roguelike elements!
ORX PC Game 2022 review:
A tower defense game where you use cards on the map using real-time costs. Like Slay the Spire, there are two branches, buying or discarding cards.
(v0.12.0.14 Update added)
Tainted Grail Conquest is an Action, Adventure, and RPG game for PC published by Awaken Realms Digital in 2021. A great hybrid card game!
Tainted Grail Conquest PC Game 2021 review:
A game with great potential and a deep atmosphere. This is the computer version of the role-playing board game Tainted Grail: The Fall of Avalon.
Devils Deck is an Action, Adventure, and Strategy game for PC published by Touch Times Studio in 2022. a hodgepodge keeps you in suspense!
Devils Deck PC Game 2022 review:
A self-sufficient game that has gone beyond the original projects and taken the “collectible card games” genre to a new level. Its uniqueness lies in the blending of genres: tabletop role-playing games, KKI, conditional platformers, and first-person adventure.